HIV-2/SIV Vpx antagonises NF-κB activation by targeting p65

Abstract Background The NF-κB family of transcription factors and associated signalling pathways are abundant and ubiquitous in human immune responses. Activation of NF-κB transcription factors by viral pathogen-associated molecular patterns, such as viral RNA and DNA, is fundamental to anti-viral i...

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Bibliographic Details
Main Authors: Douglas L. Fink, James Cai, Matthew V. X. Whelan, Christopher Monit, Carlos Maluquer de Motes, Greg J. Towers, Rebecca P. Sumner
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Retrovirology
Subjects:
Online Access:https://doi.org/10.1186/s12977-021-00586-w