HIV-2/SIV Vpx antagonises NF-κB activation by targeting p65
Abstract Background The NF-κB family of transcription factors and associated signalling pathways are abundant and ubiquitous in human immune responses. Activation of NF-κB transcription factors by viral pathogen-associated molecular patterns, such as viral RNA and DNA, is fundamental to anti-viral i...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2022-01-01
|
Series: | Retrovirology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12977-021-00586-w |