RhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling
RhoGDIα knockout mice show low male fertility and compromised spermatogenesis, with an underlying defect in F-actin cytoskeleton depolymerisation, which can be alleviated by inhibiting Rac1.
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-02-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-04579-7 |