Association of LEP G2548A and LEPR Q223R polymorphisms with cancer susceptibility: evidence from a meta-analysis.

BACKGROUND: Numerous epidemiological studies have examined associations of genetic variations in LEP (G2548A, -2548 nucleotide upstream of the ATG start site) and LEPR (Q223R, nonsynonymous SNP in exon 6) with cancer susceptibility; however, the findings are inconsistent. Therefore, we performed a m...

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Main Authors: Jing He, Bo Xi, Rikje Ruiter, Ting-Yan Shi, Mei-Ling Zhu, Meng-Yun Wang, Qiao-Xin Li, Xiao-Yan Zhou, Li-Xin Qiu, Qing-Yi Wei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3798550?pdf=render