Regulation of Metabolism by Mitochondrial MUL1 E3 Ubiquitin Ligase

Regulation of Metabolism by Mitochondrial MUL1 E3 Ubiquitin Ligase

MUL1 is a multifunctional E3 ubiquitin ligase that is involved in various pathophysiological processes including apoptosis, mitophagy, mitochondrial dynamics, and innate immune response. We uncovered a new function for MUL1 in the regulation of mitochondrial metabolism. We characterized the metaboli...

Full description

Bibliographic Details
Main Authors: Lucia Cilenti, Rohit Mahar, Jacopo Di Gregorio, Camilla T. Ambivero, Matthew E. Merritt, Antonis S. Zervos
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
MUL1
Akt2
HIF-1α
mitochondrial metabolism
metabolic flux
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.904728/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.904728/full

Similar Items