The role of HDAC6 in enhancing macrophage autophagy via the autophagolysosomal pathway to alleviate legionella pneumophila-induced pneumonia

The role of HDAC6 in enhancing macrophage autophagy via the autophagolysosomal pathway to alleviate legionella pneumophila-induced pneumonia

ABSTRACTLegionella pneumophila (L. pneumophila) is a prevalent pathogenic bacterium responsible for significant global health concerns. Nonetheless, the precise pathogenic mechanisms of L. pneumophila have still remained elusive. Autophagy, a direct cellular response to L. pneumophila infection and...

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Bibliographic Details
Main Authors: Minjia Chen, Xiuqin Cao, Ronghui Zheng, Haixia Chen, Ruixia He, Hao Zhou, Zhiwei Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Virulence
Subjects:
Histone deacetylase 6 (HDAC6)
autophagy
Legionella pneumophila
autophagyolysosomal pathway
macrophages
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2024.2327096

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https://www.tandfonline.com/doi/10.1080/21505594.2024.2327096

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