Numaswitch: an efficient high-titer expression platform to produce peptides and small proteins

Numaswitch: an efficient high-titer expression platform to produce peptides and small proteins

Abstract The production of peptides as active pharmaceutical ingredients (APIs) by recombinant technologies is of emerging interest. A reliable production platform, however, is still missing due the inherent characteristics of peptides such as proteolytic sensitivity, aggregation and cytotoxicity. W...

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Bibliographic Details
Main Authors: Bach-Ngan Nguyen, Florian Tieves, Thomas Rohr, Hilke Wobst, Felix S. Schöpf, Jóse D. Montoya Solano, Julia Schneider, Janpeter Stock, Andreas Uhde, Thomas Kalthoff, Karl Erich Jaeger, Lutz Schmitt, Christian Schwarz
Format: Article
Language:English
Published: SpringerOpen 2021-03-01
Series:AMB Express
Subjects:
Numaswitch
Switchtag
Recombinant peptides
High-titer peptide expression platform
Teriparatide
PTH(1-34)
Online Access:https://doi.org/10.1186/s13568-021-01204-w

Internet

https://doi.org/10.1186/s13568-021-01204-w

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