Apolipoprotein E derived from CD11c+ cells ameliorates atherosclerosis

Apolipoprotein E derived from CD11c+ cells ameliorates atherosclerosis

Summary: Atherosclerosis is studied in models with dysfunctional lipid homeostasis—predominantly the ApoE−/− mouse. The role of antigen-presenting cells (APCs) for lipid homeostasis is not clear. Using a LacZ reporter mouse, we showed that CD11c+ cells were enriched in aortae of ApoE−/− mice. System...

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Bibliographic Details
Main Authors: Manuela Sauter, Reinhard J. Sauter, Henry Nording, Chaolan Lin, Marcus Olbrich, Stella Autenrieth, Christian Gleissner, Martin Thunemann, Nadia Otero, Esther Lutgens, Zouhair Aherrahrou, Dennis Wolf, Lars Zender, Sven Meuth, Robert Feil, Harald F. Langer
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Immune response
Components of the immune system
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221016473

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http://www.sciencedirect.com/science/article/pii/S2589004221016473

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