Protein kinase A activation enhances β-catenin transcriptional activity through nuclear localization to PML bodies.

The Protein Kinase A (PKA) and Wnt signaling cascades are fundamental pathways involved in cellular development and maintenance. In the osteoblast lineage, these pathways have been demonstrated functionally to be essential for the production of mineralized bone. Evidence for PKA-Wnt crosstalk has be...

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Bibliographic Details
Main Authors: Mei Zhang, Emilia Mahoney, Tao Zuo, Parmeet K Manchanda, Ramana V Davuluri, Lawrence S Kirschner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4192022?pdf=render