Inhibition of vascular adhesion protein 1 protects dopamine neurons from the effects of acute inflammation and restores habit learning in the striatum

Inhibition of vascular adhesion protein 1 protects dopamine neurons from the effects of acute inflammation and restores habit learning in the striatum

Abstract Background Changes in dopaminergic neural function can be induced by an acute inflammatory state that, by altering the integrity of the neurovasculature, induces neuronal stress, cell death and causes functional deficits. Effectively blocking these effects of inflammation could, therefore,...

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Bibliographic Details
Main Authors: Serena Becchi, Alberto Buson, Bernard W. Balleine
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Journal of Neuroinflammation
Subjects:
VAP-1
Dopamine neurons
Inflammation
Dorsolateral striatum
Blood–brain barrier
Habit learning
Online Access:https://doi.org/10.1186/s12974-021-02288-8

Internet

https://doi.org/10.1186/s12974-021-02288-8

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