Acute myeloid leukemia with concurrent NPM1 and RUNX1 mutations

NPM1 mutation, as a founding genetic event, cooperates with other gene mutations, such as DNMT3A and FLT3, to promote the development of acute myeloid leukemia. NPM1 mutation, however, has been reported to be mutually exclusive with RUNX1 mutation in acute myeloid leukemia cases. In this study, we a...

Full description

Bibliographic Details
Main Authors: Zhuang Zuo, L. Jeffrey Medeiros, C. Cameron Yin
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Leukemia Research Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048923000250