Usefulness of optical coherence tomography angiography in choroidal neovascularization secondary to neovascular age-related macular degeneration

Background: Optical coherence tomography angiography (OCTA) could be a valid tool to detect choroidal neovascularization (CNV) in neovascular age-related macular degeneration (nAMD), allowing the analysis of the type, the morphology, and the extension of CNV in most of the cases. Aim: The aim of the...

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Main Authors: Mayur S Kulkarni, Mohit S Bharambe, Gauri R Kulkarni
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Journal of Clinical Ophthalmology and Research
Subjects:
Online Access:http://www.jcor.in/article.asp?issn=2320-3897;year=2020;volume=8;issue=3;spage=104;epage=108;aulast=Kulkarni
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author Mayur S Kulkarni
Mohit S Bharambe
Gauri R Kulkarni
author_facet Mayur S Kulkarni
Mohit S Bharambe
Gauri R Kulkarni
author_sort Mayur S Kulkarni
collection DOAJ
description Background: Optical coherence tomography angiography (OCTA) could be a valid tool to detect choroidal neovascularization (CNV) in neovascular age-related macular degeneration (nAMD), allowing the analysis of the type, the morphology, and the extension of CNV in most of the cases. Aim: The aim of the study was to highlight the role of OCTA in the nAMD. Setting and Design: This retrospective, cross-sectional study is done at tertiary eye care center. Materials and Methods: This study enrolled 24 patients (48 eyes). All patients underwent swept-source optical coherence tomography, swept-source OCTA, and fundus fluorescein angiography (FFA). OCTA was used to evaluate neovascular networks in terms of their type, location, and extent of visualization. Sensitivity and specificity of the method were assessed based on FFA diagnosis as the gold standard. Results: In our study, the sensitivity and specificity of OCTA in detecting CNV secondary to neovascular AMD seem to be high which were 85.1% and 80%, respectively. Conclusion: OCTA may be clinically useful to evaluate the CNV activity and response to treatment as well as to differentiate the various types of CNV in neovascular nAMD.
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spelling doaj.art-837772b9f78e44be8143e32c85ba52582022-12-21T22:32:28ZengWolters Kluwer Medknow PublicationsJournal of Clinical Ophthalmology and Research2320-38972020-01-018310410810.4103/jcor.jcor_14_19Usefulness of optical coherence tomography angiography in choroidal neovascularization secondary to neovascular age-related macular degenerationMayur S KulkarniMohit S BharambeGauri R KulkarniBackground: Optical coherence tomography angiography (OCTA) could be a valid tool to detect choroidal neovascularization (CNV) in neovascular age-related macular degeneration (nAMD), allowing the analysis of the type, the morphology, and the extension of CNV in most of the cases. Aim: The aim of the study was to highlight the role of OCTA in the nAMD. Setting and Design: This retrospective, cross-sectional study is done at tertiary eye care center. Materials and Methods: This study enrolled 24 patients (48 eyes). All patients underwent swept-source optical coherence tomography, swept-source OCTA, and fundus fluorescein angiography (FFA). OCTA was used to evaluate neovascular networks in terms of their type, location, and extent of visualization. Sensitivity and specificity of the method were assessed based on FFA diagnosis as the gold standard. Results: In our study, the sensitivity and specificity of OCTA in detecting CNV secondary to neovascular AMD seem to be high which were 85.1% and 80%, respectively. Conclusion: OCTA may be clinically useful to evaluate the CNV activity and response to treatment as well as to differentiate the various types of CNV in neovascular nAMD.http://www.jcor.in/article.asp?issn=2320-3897;year=2020;volume=8;issue=3;spage=104;epage=108;aulast=Kulkarniage-related macular degenerationchoroidal neovascularizationoptical coherence tomography angiography
spellingShingle Mayur S Kulkarni
Mohit S Bharambe
Gauri R Kulkarni
Usefulness of optical coherence tomography angiography in choroidal neovascularization secondary to neovascular age-related macular degeneration
Journal of Clinical Ophthalmology and Research
age-related macular degeneration
choroidal neovascularization
optical coherence tomography angiography
title Usefulness of optical coherence tomography angiography in choroidal neovascularization secondary to neovascular age-related macular degeneration
title_full Usefulness of optical coherence tomography angiography in choroidal neovascularization secondary to neovascular age-related macular degeneration
title_fullStr Usefulness of optical coherence tomography angiography in choroidal neovascularization secondary to neovascular age-related macular degeneration
title_full_unstemmed Usefulness of optical coherence tomography angiography in choroidal neovascularization secondary to neovascular age-related macular degeneration
title_short Usefulness of optical coherence tomography angiography in choroidal neovascularization secondary to neovascular age-related macular degeneration
title_sort usefulness of optical coherence tomography angiography in choroidal neovascularization secondary to neovascular age related macular degeneration
topic age-related macular degeneration
choroidal neovascularization
optical coherence tomography angiography
url http://www.jcor.in/article.asp?issn=2320-3897;year=2020;volume=8;issue=3;spage=104;epage=108;aulast=Kulkarni
work_keys_str_mv AT mayurskulkarni usefulnessofopticalcoherencetomographyangiographyinchoroidalneovascularizationsecondarytoneovascularagerelatedmaculardegeneration
AT mohitsbharambe usefulnessofopticalcoherencetomographyangiographyinchoroidalneovascularizationsecondarytoneovascularagerelatedmaculardegeneration
AT gaurirkulkarni usefulnessofopticalcoherencetomographyangiographyinchoroidalneovascularizationsecondarytoneovascularagerelatedmaculardegeneration