Novel Therapeutic Approaches for KRAS-Mutated Lung Cancer Involving LZTR1 Genetic Alteration

A total of 30% of lung adenocarcinoma are driven by activating KRAS mutations. The treatment options for KRAS-mutant lung cancer are still limited as a challenge for therapy is the high heterogeneity within <i>KRAS</i> mutant tumors. Co-existing genetic events alter RAS signaling, such a...

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Bibliographic Details
Main Authors: Raj N. Sewduth, Tonci Ivanisevic, Peihua Zhao, Anna A. Sablina
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Medical Sciences Forum
Subjects:
Online Access:https://www.mdpi.com/2673-9992/20/1/6