Restoration of the immune function as a complementary strategy to treat Chronic Lymphocytic Leukemia effectively

Abstract Chronic Lymphocytic Leukemia (CLL) is a hematological malignancy characterized by uncontrolled proliferation of B-cells and severe immune dysfunction. Chemo(immuno)therapies (CIT) have traditionally aimed to reduce tumor burden without fully understanding their effects on the immune system....

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Bibliographic Details
Main Authors: Carol Moreno, Cecilia Muñoz, María José Terol, José-Ángel Hernández-Rivas, Miguel Villanueva
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-021-02115-1