Reactive Bergmann glia play a central role in spinocerebellar ataxia inflammation via the JNK pathway

Abstract The spinocerebellar ataxias (SCAs) are devastating neurological diseases characterized by progressive cerebellar incoordination. While neurons bear the brunt of the pathology, a growing body of evidence suggests that glial cells are also affected. It has, however, been difficult to understa...

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Bibliographic Details
Main Authors: Chandrakanth Reddy Edamakanti, Vishwa Mohan, Puneet Opal
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-023-02801-1