Expansion of CD4+CD25-GITR+ regulatory T-cell subset in the peripheral blood of patients with primary Sjögren's syndrome: correlation with disease activity

Expansion of CD4+CD25-GITR+ regulatory T-cell subset in the peripheral blood of patients with primary Sjögren's syndrome: correlation with disease activity

Objectives: CD4+CD25high regulatory T cells (TREG) represent a suppressive T cell subset deeply involved in the modulation of immune responses and eventually in the prevention of autoimmunity. Growing evidence demonstrated that patients with autoimmune and inflammatory chronic diseases display an im...

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Bibliographic Details
Main Authors: R. Gerli, C. Riccardi, E. Lo Vaglio, S. Ronchetti, E. Bartoloni Bocci, M.G. Petrillo, O. Bistoni, G. Nocentini, A. Alunno
Format: Article
Language:English
Published: PAGEPress Publications 2012-12-01
Series:Reumatismo
Subjects:
Regulatory T cells, Sjögren’s syndrome, GITR, FoxP3
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/581

Internet

http://www.reumatismo.org/index.php/reuma/article/view/581

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