A novel test for type-I allergy based on crosslink formation of immunoglobulin-E receptors by allergen-specific immunoglobulin-E antibodies and an allergen

Abstract Detection of allergen-specific immunoglobulin E (IgE) antibodies (Abs) in serum would allow for screening of the causative allergen in patients with type-I allergy. In this study, we developed a new assay method to detect allergen-specific IgE Abs, which involved crosslinking the plural Fcε...

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Bibliographic Details
Main Authors: Yuki Koga, Soichiro Ishii, Tomoharu Yokooji, Konomi Yamamoto, Ryohei Ogino, Takanori Taogoshi, Hiroaki Matsuo
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46730-8