Network toxicology and molecular docking analyses on strychnine indicate CHRM1 is a potential neurotoxic target

Network toxicology and molecular docking analyses on strychnine indicate CHRM1 is a potential neurotoxic target

Abstract Background Improper use of strychnine can cause death. The aim of this study was to identify and evaluate toxic mechanisms of action associated with active compounds in strychnine using a network toxicology approach, and explore potential pathogenic targets. Methods In the present study, st...

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Bibliografische gegevens
Hoofdauteurs: Jialin Dai, Jiangjin Liu, Maoxin Zhang, Yanni Yu, Jie Wang
Formaat: Artikel
Taal:English
Gepubliceerd in: BMC 2022-10-01
Reeks:BMC Complementary Medicine and Therapies
Onderwerpen:
Network toxicology
Molecular docking
Strychnine
CHRM1
Online toegang:https://doi.org/10.1186/s12906-022-03753-4

Internet

https://doi.org/10.1186/s12906-022-03753-4

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