Network toxicology and molecular docking analyses on strychnine indicate CHRM1 is a potential neurotoxic target
Abstract Background Improper use of strychnine can cause death. The aim of this study was to identify and evaluate toxic mechanisms of action associated with active compounds in strychnine using a network toxicology approach, and explore potential pathogenic targets. Methods In the present study, st...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-10-01
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Series: | BMC Complementary Medicine and Therapies |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12906-022-03753-4 |