Differential induction of interferon stimulated genes between type I and type III interferons is independent of interferon receptor abundance.

Differential induction of interferon stimulated genes between type I and type III interferons is independent of interferon receptor abundance.

It is currently believed that type I and III interferons (IFNs) have redundant functions. However, the preferential distribution of type III IFN receptor on epithelial cells suggests functional differences at epithelial surfaces. Here, using human intestinal epithelial cells we could show that altho...

Full description

Bibliographic Details
Main Authors: Kalliopi Pervolaraki, Soheil Rastgou Talemi, Dorothee Albrecht, Felix Bormann, Connor Bamford, Juan L Mendoza, K Christopher Garcia, John McLauchlan, Thomas Höfer, Megan L Stanifer, Steeve Boulant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007420

Internet

https://doi.org/10.1371/journal.ppat.1007420

Similar Items