Measles virus epitope presentation by HLA: novel insights into epitope selection, dominance and microvariation
Immunity to infections with Measles Virus (MV) can involve vigorous HLA class I restricted CD8+ cytotoxic T cell (CTL) responses. MV, albeit regarded monotypic, is known to undergo molecular evolution across its RNA genome. To address which regions of the MV proteome are eligible for recognition by...
Main Authors: | Ingrid eSchellens, Hugo D Meiring, Ilka eHoof, Sanne eSpijkers, Martien C.M. Poelen, Jacqueline A.M. van Gaans-van den Brink, Ana I Costa, Harry eVennema, Can eKesmir, Debbie eVan Baarle, Cecile A.C.M. Van Els |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-11-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00546/full |
Similar Items
-
HLA Preferences for Conserved Epitopes: A Potential Mechanism for Hepatitis C Clearance
by: Xiangyu eRao, et al.
Published: (2015-10-01) -
Complementarity of binding motifs is a general property of HLA-A and HLA-B molecules and does not seem to effect HLA haplotype composition
by: Xiangyu eRao, et al.
Published: (2013-11-01) -
HLA-DO and its role in MHC Class II antigen presentation
by: Yuri O Poluektov, et al.
Published: (2013-08-01) -
CD4+ T cells targeting dominant and cryptic epitopes from Bacillus anthracis Lethal Factor
by: Stephanie eAscough, et al.
Published: (2016-01-01) -
MHC Class II Auto-antigen Processing and Presentation is Unconventional
by: Scheherazade eSadegh-Nasseri, et al.
Published: (2015-07-01)