Vertical transmission of attaching and invasive E. coli from the dam to neonatal mice predisposes to more severe colitis following exposure to a colitic insult later in life.

Vertical transmission of attaching and invasive E. coli from the dam to neonatal mice predisposes to more severe colitis following exposure to a colitic insult later in life.

The gastrointestinal microbiota begins to be acquired at birth and continually matures through early adolescence. Despite the relevance for gut health, few studies have evaluated the impact of pathobiont colonization of neonates on the severity of colitis later in life. LF82 is an adherent invasive...

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Bibliographic Details
Main Authors: Meghan Wymore Brand, Alexandra L Proctor, Jesse M Hostetter, Naihui Zhou, Iddo Friedberg, Albert E Jergens, Gregory J Phillips, Michael J Wannemuehler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0266005

Internet

https://doi.org/10.1371/journal.pone.0266005

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