HDS screening with patient-derived primary cells guided individualized therapy for esophageal squamous cell carcinoma–in vivo and vitro

HDS screening with patient-derived primary cells guided individualized therapy for esophageal squamous cell carcinoma–in vivo and vitro

ObjectiveTo analyze and evaluate the role of the High-throughput Drug Sensitivity (HDS) screening strategy in identifying highly sensitive drugs against esophageal squamous cell carcinoma (ESCC).MethodsA total of 80 patients with progressive ESCC were randomly divided into the observation (40 cases)...

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Bibliographic Details
Main Authors: Xing He, Hezhong Yan, Jie Hu, Xiaowei Duan, Mingjin Zhang, Haiqing Li, Jiaoxue Wang, Qian Gao, Senyuan Yu, Xilu Hou, Guobin Liao, Shicun Guo, Jin Li, Yurong Ge, Xiaolan Chen, Wenchao Wang, Jun Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Medicine
Subjects:
esophageal squamous cell carcinoma
high-throughput drug sensitivity screening technology
drug sensitivity
patient-derived tumor xenografts
therapeutic efficacy
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1212851/full

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https://www.frontiersin.org/articles/10.3389/fmed.2023.1212851/full

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