Convection Enhanced Delivery in the Setting of High-Grade Gliomas

Convection Enhanced Delivery in the Setting of High-Grade Gliomas

Development of effective treatments for high-grade glioma (HGG) is hampered by (1) the blood–brain barrier (BBB), (2) an infiltrative growth pattern, (3) rapid development of therapeutic resistance, and, in many cases, (4) dose-limiting toxicity due to systemic exposure. Convection-enhanced delivery...

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Bibliographic Details
Main Authors: Chibueze D. Nwagwu, Amanda V. Immidisetti, Michael Y. Jiang, Oluwasegun Adeagbo, David C. Adamson, Anne-Marie Carbonell
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceutics
Subjects:
glioblastoma
high-grade glioma
refractory glioma
direct delivery
convection enhanced delivery
neuro-oncology
Online Access:https://www.mdpi.com/1999-4923/13/4/561

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https://www.mdpi.com/1999-4923/13/4/561

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