A different vision of translational research in biomarker discovery: a pilot study on circulatory mitochondrial proteins as Parkinson’s disease potential biomarkers

A different vision of translational research in biomarker discovery: a pilot study on circulatory mitochondrial proteins as Parkinson’s disease potential biomarkers

Abstract Background The identification of circulating biomarkers that closely correlate with Parkinson’s Disease (PD) has failed several times in the past. Nevertheless, in this pilot study, a translational approach was conducted, allowing the evaluation of the plasma levels of two mitochondrial-rel...

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Bibliographic Details
Main Authors: Sandra I. Anjo, Patrícia Valério dos Santos, Luiza Rosado, Graça Baltazar, Inês Baldeiras, Diana Pires, Andreia Gomes, Cristina Januário, Miguel Castelo-Branco, Mário Grãos, Bruno Manadas
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Translational Neurodegeneration
Subjects:
Mitochondrial-related proteins
SWATH-MS
Parkinson’s disease
Biomarker discovery
Blood-biomarker
Secretomes
Online Access:http://link.springer.com/article/10.1186/s40035-020-00188-0

Internet

http://link.springer.com/article/10.1186/s40035-020-00188-0

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