Generation of human induced pluripotent stem cell-derived cerebral organoids for cellular and molecular characterization

Generation of human induced pluripotent stem cell-derived cerebral organoids for cellular and molecular characterization

Summary: Human induced pluripotent stem cell (hiPSC)-derived cerebral organoids (COs) can serve as an in vitro model for studying normal and pathologic human brain development. Here, we optimized existing protocols to streamline the generation of forebrain COs from hiPSCs. We employ these COs to def...

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Bibliographic Details
Main Authors: Corina Anastasaki, Anna F. Wilson, Alexander S. Chen, Michelle L. Wegscheid, David H. Gutmann
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:STAR Protocols
Subjects:
Cell Biology
Cell culture
Developmental biology
Health Sciences
Neuroscience
Stem Cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722000533

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http://www.sciencedirect.com/science/article/pii/S2666166722000533

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