Functional reconstruction of injured corpus cavernosa using 3D-printed hydrogel scaffolds seeded with HIF-1α-expressing stem cells

Injury of corpus cavernosa results in erectile dysfunction, and repair leading to restoration of function is difficult. Here the authors construct 3D printed hydrogel constructs seeded with HIF-1α-expressing muscle derived stem cells to restore corpus function in a rabbit model.

Bibliographic Details
Main Authors: Geng An, Feixiang Guo, Xuemin Liu, Zhifang Wang, Ye Zhu, Yong Fan, Chengkai Xuan, Yan Li, Hongkai Wu, Xuetao Shi, Chuanbin Mao
Format: Article
Language:English
Published: Nature Portfolio 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16192-x