Study on the Alkylation Reactions of N(7)-Unsubstituted 1,3-Diazaoxindoles

Study on the Alkylation Reactions of N(7)-Unsubstituted 1,3-Diazaoxindoles

The chemistry of the 5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one (1,3-diazaoxindole) compound family, possessing a drug-like scaffold, is unexplored. In this study, the alkylation reactions of N(7)-unsubstituted 5-isopropyl-1,3-diazaoxindoles bearing various substituents at the C(2) position have b...

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Bibliographic Details
Main Authors: Eszter Kókai, Judit Halász, András Dancsó, József Nagy, Gyula Simig, Balázs Volk
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Molecules
Subjects:
alkylation
lithiation
regioselectivity
1,3-diazaoxindoles
by-products
Online Access:http://www.mdpi.com/1420-3049/22/5/846

Internet

http://www.mdpi.com/1420-3049/22/5/846

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