HCV treatment outcome depends on SNPs of IFNL3-Gene polymorphisms (rs12979860) and cirrhotic changes in liver parenchyma

HCV treatment outcome depends on SNPs of IFNL3-Gene polymorphisms (rs12979860) and cirrhotic changes in liver parenchyma

Background and objective: The allelic discrimination of IFNL3-(rs12979860 C > T) polymorphism reveals ambiguous associations with the effectiveness of oral HCV treatment. Solitary intra peripheral-blood-mononuclear-cells (PBMCs) HCV-RNA antisense-strands are independently detected in naïve and ex...

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Bibliographic Details
Main Authors: Mohamed Darwish Ahmed Abd Alla, Reham M. Dawood, Hassan Abd EL-Hafeth Rashed, Yasser Mohammed El-Dessouky, Galal AbdElhameed AbuFarrag, Islam Abdelmawla Emran Ammar, Mohamed Mahmoud Abdel-Halim Mahmoud, Ghada M. Salum, Mohamed Zakaria Abu-Amer, Mohamed Abd elrafaa Hassan Sekeen, Mohamed Mousa Ibraheem Heggazy, Ahmed Mohamed Abdulhamid Altanbouly, Mai Abd El-Meguid, Mostafa K. El Awady
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
IFNL3-Gene-SNPs
DAAs
PBMCs-PCR
HCV-Hepatic-changes
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023084025

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http://www.sciencedirect.com/science/article/pii/S2405844023084025

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