Immunogenicity of Potential CD4+ and CD8+ T Cell Epitopes Derived From the Proteome of Leishmania braziliensis

Immunogenicity of Potential CD4+ and CD8+ T Cell Epitopes Derived From the Proteome of Leishmania braziliensis

Background: A safe and effective vaccine against human leishmaniasis still requires the identification of better antigens for immunization and adequate models to evaluate the immune response. To support vaccine development, this work tested the immunogenicity of 10 different peptides derived from th...

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Bibliographic Details
Main Authors: Rafael de Freitas e Silva, Beatriz Coutinho de Oliveira, Ailton Alvaro da Silva, Maria Carolina Accioly Brelaz de Castro, Luiz Felipe Gomes Rebello Ferreira, Marcelo Zaldini Hernandes, Maria Edileuza Felinto de Brito, Osvaldo Pompílio de-Melo-Neto, Antônio Mauro Rezende, Valéria Rêgo Alves Pereira
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
neglected diseases
cutaneous leishmaniasis
Leishmania (Viannia) braziliensis
immunogenicity
CD4+ CD8+ T cell epitopes
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03145/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.03145/full

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