Serum and mucosal antibody-mediated protection and identification of asymptomatic respiratory syncytial virus infection in community-dwelling older adults in Europe

IntroductionRespiratory syncytial virus (RSV) causes acute respiratory tract infection (ARTI) and reinfects adults throughout life, posing a risk for hospitalization in older adults (>60 years) with frailty and comorbidities.MethodsTo investigate serum and mucosal antibodies for protection ag...

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Main Authors: Deniz Öner, Charlotte Vernhes, Sunita Balla-Jhagjhoorsingh, Annick Moureau, Marjolein Crabbe, Bruno Salaun, Arangassery Rosemary Bastian, Kim Thys, Jonathan De Smedt, Salo N. Ooft, Koos Korsten, Niels Adriaenssens, Samuel Coenen, Christopher C. Butler, Theo J. M. Verheij, Simon B. Drysdale, Joanne G. Wildenbeest, Andrew J. Pollard, Peter J. M. Openshaw, Louis Bont, Jeroen Aerssens
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1448578/full