Identification, Selection and Immune Assessment of Liver Stage CD8 T Cell Epitopes From Plasmodium falciparum

Identification, Selection and Immune Assessment of Liver Stage CD8 T Cell Epitopes From Plasmodium falciparum

Immunization with radiation-attenuated sporozoites (RAS) has been shown to protect against malaria infection, primarily through CD8 T cell responses, but protection is limited based on parasite strain. Therefore, while CD8 T cells are an ideal effector population target for liver stage malaria vacci...

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Bibliographic Details
Main Authors: Kenneth D. Tucker, Brian C. Schanen, Timothy W. Phares, Emily Sassano, Frances E. Terry, Pooja Hindocha, Leonard Moise, Vinayaka Kotraiah, William D. Martin, Anne S. De Groot, Donald R. Drake, Gabriel M. Gutierrez, Amy R. Noe
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
malaria
vaccine
epitopes
CSP
SPECT-2
MIMIC
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.684116/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.684116/full

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