Anti-S100A4 antibody administration alleviates bronchial epithelial–mesenchymal transition in asthmatic mice

We elucidated the effect of S100A4 on airway remodeling by regulating airway inflammation and epithelial–mesenchymal transition (EMT) in mouse models of asthma. Asthmatic mouse models were established by sensitization and challenged with ovalbumin (OVA). Anti-S100A4 antibody or control IgG antibody...

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Bibliographic Details
Main Authors: Liu Shuang, Liu Min, Zhong Jinnan, Chen Shi, Wang Ziming, Gao Xiaoyan, Li Fajiu
Format: Article
Language:English
Published: De Gruyter 2023-10-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2022-0622