The immune modulatory effects of umbilical cord-derived mesenchymal stromal cells in severe COVID-19 pneumonia

The immune modulatory effects of umbilical cord-derived mesenchymal stromal cells in severe COVID-19 pneumonia

Abstract Coronavirus disease 2019 (COVID-19) may result in a life-threatening condition due to a hyperactive immune reaction to severe acute respiratory syndrome-coronavirus-2 infection, for which no effective treatment is available. Based on the potent immunomodulatory properties of mesenchymal str...

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Bibliographic Details
Main Authors: Rachele Ciccocioppo, Davide Gibellini, Giuseppe Astori, Martina Bernardi, Angela Bozza, Katia Chieregato, Francesca Elice, Stefano Ugel, Simone Caligola, Francesco De Sanctis, Stefania Canè, Alessandra Fiore, Rosalinda Trovato, Antonio Vella, Varvara Petrova, Giuseppe Amodeo, Monica Santimaria, Annarita Mazzariol, Luca Frulloni, Marco Ruggeri, Enrico Polati, Vincenzo Bronte
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Stem Cell Research & Therapy
Subjects:
COVID-19
Cytokines
Inflammatory response
Mesenchymal stromal cells
ScRNA-seq
Online Access:https://doi.org/10.1186/s13287-021-02376-9

Internet

https://doi.org/10.1186/s13287-021-02376-9

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