Secreted aspartyl proteinase (PbSap) contributes to the virulence of Paracoccidioides brasiliensis infection.

Paracoccidioidomycosis (PCM) is the most prevalent deep mycosis in Latin America and is caused by fungi from the Paracoccidioides genus. Virulence factors are important fungal characteristics that support the development of disease. Aspartyl proteases (Saps) are virulence factors in many human funga...

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Bibliographic Details
Main Authors: Daniele Gonçalves Castilho, Alison Felipe Alencar Chaves, Marina Valente Navarro, Palloma Mendes Conceição, Karen Spadari Ferreira, Luiz Severino da Silva, Patricia Xander, Wagner Luiz Batista
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6177206?pdf=render