Potential Antimetastatic Effect of Timosaponin AIII against Human Osteosarcoma Cells through Regulating the Integrin/FAK/Cofilin Axis

Potential Antimetastatic Effect of Timosaponin AIII against Human Osteosarcoma Cells through Regulating the Integrin/FAK/Cofilin Axis

Timosaponin AIII (TSAIII) is a steroidal saponin which demonstrates anti-tumour activities. However, the effect of TSAIII on human osteosarcoma cells remains largely unknown. In this study, we demonstrated that TSAIII exerted a significant inhibitory effect on the distribution of cytoskeletal F-acti...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Yi-Hsien Hsieh, Wen-Hung Hsu, Shun-Fa Yang, Chung-Jung Liu, Ko-Hsiu Lu, Pei-Han Wang, Renn-Chia Lin
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: MDPI AG 2021-03-01
Sraith:Pharmaceuticals
Ábhair:
TSAIII
human osteosarcoma cell lines
cofilin
metastasis
F-actin
Rochtain ar líne:https://www.mdpi.com/1424-8247/14/3/260

Ar líne

https://www.mdpi.com/1424-8247/14/3/260

Míreanna comhchosúla