ChAdOx1 NiV vaccination protects against lethal Nipah Bangladesh virus infection in African green monkeys

Abstract Nipah virus (NiV) is a highly pathogenic and re-emerging virus, which causes sporadic but severe infections in humans. Currently, no vaccines against NiV have been approved. We previously showed that ChAdOx1 NiV provides full protection against a lethal challenge with NiV Bangladesh (NiV-B)...

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Bibliographic Details
Main Authors: Neeltje van Doremalen, Victoria A. Avanzato, Kerry Goldin, Friederike Feldmann, Jonathan E. Schulz, Elaine Haddock, Atsushi Okumura, Jamie Lovaglio, Patrick W. Hanley, Kathleen Cordova, Greg Saturday, Emmie de Wit, Teresa Lambe, Sarah C. Gilbert, Vincent J. Munster
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-022-00592-9