Hyperinsulinemia rather than insulin resistance itself induces blood pressure elevation in high fat diet-fed rats

Objective To investigate if insulin resistance per se or the accompanying hyperinsulinemia induced hypertension and its underlying mechanisms. Methods Sprague-Dawley rats were randomized into normal diet-fed group (ND group) and high-fat diet-fed group (HFD group). Then, the HFD group was further ra...

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Bibliographic Details
Main Authors: Hui Wang, Yaqiang Tian, Yanyan Chen, Xiaoxia Shen, Lin Pan, Guangwei Li
Format: Article
Language:English
Published: Taylor & Francis Group 2020-10-01
Series:Clinical and Experimental Hypertension
Subjects:
Online Access:http://dx.doi.org/10.1080/10641963.2020.1756316