An improved algorithm for flux variability analysis

Abstract Flux balance analysis (FBA) is an optimization based approach to find the optimal steady state of a metabolic network, commonly of microorganisms such as yeast strains and Escherichia coli. However, the resulting solution from an FBA is typically not unique, as the optimization problem is,...

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Bibliographic Details
Main Authors: Dustin Kenefake, Erick Armingol, Nathan E. Lewis, Efstratios N. Pistikopoulos
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-022-05089-9