Correlation between Dopamine Transporter Degradation and Striatocortical Network Alteration in Parkinson’s Disease

Correlation between Dopamine Transporter Degradation and Striatocortical Network Alteration in Parkinson’s Disease

The association between dopamine neuron loss and functional change in the striatocortical network was analyzed in 31 patients with Parkinson’s disease (PD) [mean disease duration 4.03 ± 4.20 years; Hoehn and Yahr (HY) stage 2.2 ± 1.2] and 37 age-matched normal control subjects. We performed 99mTc-TR...

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Bibliographic Details
Main Authors: Wei-Che Lin, Hsiu-Ling Chen, Tun-Wei Hsu, Chien-Chin Hsu, Yung-Cheng Huang, Nai-Wen Tsai, Cheng-Hsien Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Neurology
Subjects:
dopamine transporter imaging
functional connectivity
movement disorder
magnetic resonance imaging
parkinsonism
99mTc-TRODAT-1 SPECT/CT
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00323/full

Internet

http://journal.frontiersin.org/article/10.3389/fneur.2017.00323/full

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