Anthrax toxin uptake by primary immune cells as determined with a lethal factor-beta-lactamase fusion protein.
BACKGROUND:To initiate infection, Bacillus anthracis needs to overcome the host innate immune system. Anthrax toxin, a major virulence factor of B. anthracis, impairs both the innate and adaptive immune systems and is important in the establishment of anthrax infections. METHODOLOGY/PRINCIPAL FINDIN...
Principais autores: | , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Public Library of Science (PLoS)
2009-11-01
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coleção: | PLoS ONE |
Acesso em linha: | http://europepmc.org/articles/PMC2775957?pdf=render |