Anthrax toxin uptake by primary immune cells as determined with a lethal factor-beta-lactamase fusion protein.

BACKGROUND:To initiate infection, Bacillus anthracis needs to overcome the host innate immune system. Anthrax toxin, a major virulence factor of B. anthracis, impairs both the innate and adaptive immune systems and is important in the establishment of anthrax infections. METHODOLOGY/PRINCIPAL FINDIN...

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Detalhes bibliográficos
Principais autores: Haijing Hu, Stephen H Leppla
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2009-11-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC2775957?pdf=render