Oleuropein confers neuroprotection against rotenone-induced model of Parkinson’s disease via BDNF/CREB/Akt pathway

Oleuropein confers neuroprotection against rotenone-induced model of Parkinson’s disease via BDNF/CREB/Akt pathway

Abstract Major pathological features of Parkinson’s disease (PD) include increase in oxidative stress leading to the aggregation of α-synuclein, mitochondrial dysfunction and apoptosis of dopaminergic neurons. In addition, downregulation of the expression of neurotrophic factors like-Brain Derived N...

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Bibliographic Details
Main Authors: Richa Singh, Walia Zahra, Saumitra Sen Singh, Hareram Birla, Aaina Singh Rathore, Priyanka Kumari Keshri, Hagera Dilnashin, Shekhar Singh, Surya Pratap Singh
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29287-4

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https://doi.org/10.1038/s41598-023-29287-4

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