Oleuropein confers neuroprotection against rotenone-induced model of Parkinson’s disease via BDNF/CREB/Akt pathway
Abstract Major pathological features of Parkinson’s disease (PD) include increase in oxidative stress leading to the aggregation of α-synuclein, mitochondrial dysfunction and apoptosis of dopaminergic neurons. In addition, downregulation of the expression of neurotrophic factors like-Brain Derived N...
Main Authors: | Richa Singh, Walia Zahra, Saumitra Sen Singh, Hareram Birla, Aaina Singh Rathore, Priyanka Kumari Keshri, Hagera Dilnashin, Shekhar Singh, Surya Pratap Singh |
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Format: | Article |
Jezik: | English |
Izdano: |
Nature Portfolio
2023-02-01
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Serija: | Scientific Reports |
Online dostop: | https://doi.org/10.1038/s41598-023-29287-4 |
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