An intronic LINE-1 regulates IFNAR1 expression in human immune cells

Abstract Background Despite their origins as selfish parasitic sequences, some transposons in the human genome have been co-opted to serve as regulatory elements, contributing to the evolution of transcriptional networks. Most well-characterized examples of transposon-derived regulatory elements der...

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Bibliographic Details
Main Authors: Carmen A. Buttler, Daniel Ramirez, Robin D. Dowell, Edward B. Chuong
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Mobile DNA
Subjects:
Online Access:https://doi.org/10.1186/s13100-023-00308-3