STING mediates experimental osteoarthritis and mechanical allodynia in mouse

Abstract Background This study was performed to develop therapeutic targets of osteoarthritis (OA) that can be targeted to alleviate OA development (i.e., cartilage destruction) and relieve the OA-associated joint pain. Methods The candidate molecule, STING (stimulator of interferon genes, encoded b...

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Bibliographic Details
Main Authors: Youngnim Shin, Deborah Cho, Seul Ki Kim, Jang-Soo Chun
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Arthritis Research & Therapy
Online Access:https://doi.org/10.1186/s13075-023-03075-x