Vitamin D supplementation alleviates insulin resistance in prediabetic rats by modifying IRS-1 and PPARγ/NF-κB expressions

Vitamin D supplementation alleviates insulin resistance in prediabetic rats by modifying IRS-1 and PPARγ/NF-κB expressions

BackgroundPrediabetes is a condition of intermediate hyperglycemia that may progress to type 2 diabetes. Vitamin D deficiency has been frequently linked to insulin resistance and diabetes. The study aimed to investigate the role of D supplementation and its possible mechanism of action on insulin re...

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Bibliographic Details
Main Authors: Desak Gede Budi Krisnamurti, Melva Louisa, Erni H. Poerwaningsih, Tri Juli Edi Tarigan, Vivian Soetikno, Heri Wibowo, Christian Marco Hadi Nugroho
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Endocrinology
Subjects:
diabetes mellitus
high-fat diet
25-hydroxyergocalciferol
inflammation
insulin resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1089298/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1089298/full

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