Glutathione disulfide sensitizes hepatocytes to TNFα-mediated cytotoxicity via IKK-β S-glutathionylation: a potential mechanism underlying non-alcoholic fatty liver disease

Glutathione disulfide sensitizes hepatocytes to TNFα-mediated cytotoxicity via IKK-β S-glutathionylation: a potential mechanism underlying non-alcoholic fatty liver disease

Fatty liver disease: spent antioxidant and liver cell death An imbalance between ROS and antioxidant molecules, induced by a high-fat diet, is a major contributor to non-alcoholic fatty liver disease in a mouse model. Dr. Zhenyuan Song from the University of Illinois at Chicago, USA, and colleagues...

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Bibliographic Details
Main Authors: Xiaobing Dou, Songtao Li, Linfeng Hu, Lei Ding, Yue Ma, Wang Ma, Hui Chai, Zhenyuan Song
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-017-0013-x

Internet

https://doi.org/10.1038/s12276-017-0013-x

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