Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology

Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology

Abstract Serum liver enzyme concentrations are the most frequently-used laboratory markers of liver disease, a major cause of mortality. We conduct a meta-analysis of genome-wide association studies of liver enzymes from UK BioBank and BioBank Japan. We identified 160 previously-unreported independe...

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Bibliographic Details
Main Authors: Vincent L. Chen, Xiaomeng Du, Yanhua Chen, Annapurna Kuppa, Samuel K. Handelman, Rishel B. Vohnoutka, Patricia A. Peyser, Nicholette D. Palmer, Lawrence F. Bielak, Brian Halligan, Elizabeth K. Speliotes
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20870-1

Internet

https://doi.org/10.1038/s41467-020-20870-1

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