Role of movement in long-term basal ganglia changes: implications for abnormal motor responses

Abnormal involuntary movements and dyskinesias elicited by drugs that stimulate dopamine receptors in the basal ganglia are a major issue in the management of Parkinson’s disease (PD). Preclinical studies in dopamine-denervated animals have contributed to the modeling of these abnormal movements, bu...

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Bibliographic Details
Main Authors: Nicola eSimola, Micaela eMorelli, Giuseppe eFrazzitta, Lucia eFrau
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Computational Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncom.2013.00142/full