Connecting a disconnected trial network with a new trial: optimizing the estimation of a comparative effect in a network meta-analysis
Abstract Background In network meta-analysis, estimation of a comparative effect can be performed for treatments that are connected either directly or indirectly. However, disconnected trial networks may arise, which poses a challenge to comparing all available treatments of interest. Several modeli...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-04-01
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Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12874-023-01896-7 |