Identification and Functional Analysis of Two Novel Genes—Geranylgeranyl Pyrophosphate Synthase Gene (<i>AlGGPPS</i>) and Isopentenyl Pyrophosphate Isomerase Gene (<i>AlIDI</i>)—from <i>Aurantiochytrium limacinum</i> Significantly Enhance De Novo β-Carotene Biosynthesis in <i>Escherichia coli</i>

Identification and Functional Analysis of Two Novel Genes—Geranylgeranyl Pyrophosphate Synthase Gene (<i>AlGGPPS</i>) and Isopentenyl Pyrophosphate Isomerase Gene (<i>AlIDI</i>)—from <i>Aurantiochytrium limacinum</i> Significantly Enhance De Novo β-Carotene Biosynthesis in <i>Escherichia coli</i>

Precursor regulation has been an effective strategy to improve carotenoid production and the availability of novel precursor synthases facilitates engineering improvements. In this work, the putative geranylgeranyl pyrophosphate synthase encoding gene (<i>AlGGPPS</i>) and isopentenyl pyr...

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Bibliographic Details
Main Authors: Shitao Shi, Yi Chang, Jinhui Yu, Hui Chen, Qiang Wang, Yuping Bi
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Marine Drugs
Subjects:
<i>Aurantiochytrium limacinum</i>
terpenoid precursor
geranylgeranyl pyrophosphate synthase (GGPPS)
isopentenyl pyrophosphate isomerase (IDI)
β-carotene biosynthesis
Online Access:https://www.mdpi.com/1660-3397/21/4/249

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https://www.mdpi.com/1660-3397/21/4/249

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