p73α1, an Isoform of the p73 Tumor Suppressor, Modulates Lipid Metabolism and Cancer Cell Growth via Stearoyl-CoA Desaturase-1

p73α1, an Isoform of the p73 Tumor Suppressor, Modulates Lipid Metabolism and Cancer Cell Growth via Stearoyl-CoA Desaturase-1

Altered lipid metabolism is a hallmark of cancer. p73, a p53 family member, regulates cellular processes and is expressed as multiple isoforms. However, the role of p73 in regulating lipid metabolism is not well-characterized. Previously, we found that loss of p73 exon 12 (<i>E12</i>) le...

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Bibliographic Details
Main Authors: Zachary Rabow, Kyra Laubach, Xiangmudong Kong, Tong Shen, Shakur Mohibi, Jin Zhang, Oliver Fiehn, Xinbin Chen
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
p73 isoforms
the p53 family
Stearoyl-CoA Desaturase
lipid metabolism
Kennedy pathway
Online Access:https://www.mdpi.com/2073-4409/11/16/2516

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https://www.mdpi.com/2073-4409/11/16/2516

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